Practical Guidelines for Economic Evaluations Alongside Equivalence Trials
نویسندگان
چکیده
منابع مشابه
Using resource use logs to reduce the amount of missing data in economic evaluations alongside trials.
OBJECTIVES Economic evaluations alongside randomized controlled trials that collect data using patient-completed questionnaires are prone to missing data. Our objective was to determine whether giving patients a resource use log (RUL) at baseline would improve the odds of completing questions in a follow-up resource use questionnaire (RUQ) and to identify patients' views on RUL's usefulness and...
متن کاملDesign and analysis issues for economic analysis alongside clinical trials.
INTRODUCTION Clinical trials can offer a valuable and efficient opportunity to collect the health resource use and outcomes data for economic evaluation. However, economic and clinical studies differ fundamentally in the question they seek to answer. OBJECTIVE The design and analysis of trial-based cost-effectiveness studies require special consideration, which are reviewed in this article. ...
متن کاملEconomic evaluations in cancer clinical trials
Authors: Stephen Goodall and Rosalie Viney Prepared: July 2011 SUMMARY • The aim of economic evaluation is to inform clinical and health system decision making and policy • Every time a decision is made about a new technology or treatment, a decision is also made about resource allocation • Economic evaluation is a formal and systematic comparison of the costs and benefits associated with two o...
متن کاملEconomic evaluation alongside pragmatic randomised trials: developing a standard operating procedure for clinical trials units
BACKGROUND There is wide recognition that pragmatic randomised trials are the best vehicle for economic evaluation. This is because trials provide the best chance of ensuring internal validity, not least through the rigorous prospective collection of patient-specific data. Furthermore the marginal cost of collecting economic data alongside clinical data is typically modest. UK Clinical Research...
متن کاملPractical guidelines for multiplicity adjustment in clinical trials.
Multiplicity in clinical trials may appear under several different guises: multiple endpoints, multiple treatment arm comparisons, and multiple looks at the data during interim monitoring, to name a few. It is well recognized by statisticians and nonstatisticians alike that multiplicity inflates the type I error rate of the experiment, and this has prompted the development of many multiple comp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Value in Health
سال: 2008
ISSN: 1098-3015
DOI: 10.1111/j.1524-4733.2007.00245.x